Thursday, May 5, 2016
Monograph of Paeonia lactiflora
Paeonia lactiflora
Photo By Ulf Eliasson - Own work, CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=1385608
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Also known as Paeonia, White PeonyPeony is sometimes referred to red peony or white peony. This does not refer to the colour of the flowers, which vary in colour and shape, but to the colour of root after processing. |
Family Paeoniaceae |
Part used: Root
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Active constituents
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Paeoniflorin • Paeonilactones
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According to Traditional Chinese medicine the (White) peony root is mild cold in nature, bitter and sour in flavour. |
Therapeutic Actions:
Blood tonic (traditional)
Astringent/styptic
Antispasmodic8
Analgesic8
Spasmolytic1
Mild skeletal
muscle relaxant1, 3
Anticonvulsant1
Anti-inflammatory1,8,9
Cognitive enhancer 1/Nootropic/Neuroprotective9
Immunomodulator8/Anti-allergic
6
Antioxidant8,9
Mild sedative
HPO Axis Regulator2,7
Ovarian tonic7
Uterine Tonic
Anti-androgenic7
Dopaminergic
Contemporary Studies
Rat studies show
that due to the presence of constituent paeoniflorin there is an
anti-oxytocic action on the uterine muscles3
Paeoniflorin is a
mild vasodilator and smooth muscle relaxant. It has shown to inhibit twitch
responses of skeletal muscle from direct and indirect stimulation3
Antiviral
specifically human rhinoviruses (HRV-2 and HRV-4)5
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Indications for use
Polycystic Ovarian Sydrome1/Disease7
Endometriosis2
/ Menstrual dysfunction1
Assists
in memory and learning1
Skeletal
muscle cramps and spasm1,8
Angina1
Epilepsy1
Autoimmune Disease
TCM:
Swellings, trauma, abscess, boils, swollen painful eyes, Nosebleed,
haematemesis
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Dosage1:2 Liquid Extract 4.5 - 8.5 ml per day / 30-60ml per week1Combinations
With
Glycyrrhiza glabra for PCOS/PCOD and associated signs and symptoms
eg.dysmenorrhoea1,3
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No known Cautions or Contra-indications |
References
1. Bone
K. A Clinical Guide to Blending Liquid
Herbs. St Louis: Elsevier; 2003. p458- 61
2. Sarris J,
Wardle J. Clinical Naturopathy: An evidence-based guide to practice.
Chatswood, NSW: Elsevier; 2010. pp 376-396; 466;
3. Trickey
R. Women, Hormones and the menstrual cycle. 3rd edition. Victoria,
Australia: Trickey enterprises; 2011 p882-3, p241
4. Peony (Paeonia SPP). Monograph. Alternative Medicine Review, October
2001. 6(5), 495+.
Cited from Academic OneFile.
Web. 06 Apr. 2016.
5. Ngan,
Luong Thi My et al. Antiviral Activity and Possible Mechanism of Action of
Constituents Identified in Paeonia Lactiflora Root toward Human Rhinoviruses.
Ed. Krzysztof Pyrc. PLoS ONE 10.4 (2015): e0121629. PMC. Web. 28 Apr. 2016.
6. Yan-Hong
Shi, Shu Zhu, Yue-Wei Ge, Yu-Min He, Kohei Kazuma, Zhengtao Wang, Kayo
Yoshimatsu, Katsuko Komatsu. Monoterpene derivatives with anti-allergic activity
from red peony root, the root of Paeonia lactiflora. Fitoterapia. v108.
January 2016. Pages 55-61, ISSN 0367-326X,
(http://dx.doi.org/10.1016/j.fitote.2015.11.011.(http://www.sciencedirect.com/science/article/pii/S0367326X15301209)
7. Smith, P
W. PCOS: a common endocrine disorder. Townsend Letter. Apr. 2015 (2016 Apr 6)
p61. Academic OneFile. Web.
URL(http://go.galegroup.com.ezproxy.think.edu.au/ps/i.do?id=GALE%7CA409236867&v=2.1&u=think&it=r&p=AONE&sw=w&asid=b32bcd69618e6be90705358bb8cc2cc6)
8. He D-Y,
Dai S-M. Anti-Inflammatory and Immunomodulatory Effects of Paeonia Lactiflora
Pall.: a Traditional Chinese Herbal Medicine. Frontiers in Pharmacology.
2011. (cited 2016 Apr 6) 2 (10). doi:10.3389/fphar.2011.00010.
9. Nam, K.,
Woo, B.-C., Moon, S.-K., Park, S.-U., Park, J.-Y., Hwang, J.-W., ...Lee, E.
(2013). Paeonol attenuates inflammation-mediated neurotoxicity and microglial
activation. Neural Regeneration Research. 8(18). p1637. Retrieved 2016-04-06
from (http://go.galegroup.com.ezproxy.think.edu.au/ps/i.do?id=GALE%7CA383570255&v=2.1&u=think&it=r&p=AONE&sw=w&asid=8f18ba20fcc7b464a4f5f6594dc08faa)
10. Takeuchi
T, Nishii O, Okamura T, Yaginuma T: Effect of traditional herbal medicine,
shakuyaku-kanzo-to on total and free serum testosterone levels. Am J Chin Med
1989, 17(1-2):35–44
11. Ushiroyama
T, Ikeda A, Sakai M, Hosotani T, Suzuki Y, Tsubokura S, Ueki M. Effects of
unkei-to, an herbal medicine, on endocrine function and ovulation in women
with high basal levels of luteinizing hormone secretion. J Reprod Med 2001(Cited
2016 Apr 5) 46(5). pp451–456. 58.
12. Yaginuma TI, Yasui R, Arai H, Kawabata T.
Effect of traditional herbal medicine on serum testosterone levels and its
induction of regular ovulation in hyperandrogenic and oligomenorrheic women.
Nippon Sanka Fujinka Gakkai Zasshi 1982 (Cited 2016 Apr 5) 34(7):939
13. Arentz, S., Abbott, J. A., Smith, C. A.,
& Bensoussan, A. Herbal medicine for the management of polycystic ovary
syndrome (PCOS) and associated oligo/amenorrhoea and hyperandrogenism; a
review of the laboratory evidence for effects with corroborative clinical
findings. BMC Complementary and Alternative Medicine 14 (2014) (cited 20 Apr
2016 web) 511. Academic OneFile.
URL(http://go.galegroup.com.ezproxy.think.edu.au/ps/i.do?id=GALE%7CA401166382&v=2.1&u=think&it=r&p=AONE&sw=w&asid=20da78983c4907ccf1ef8db0ac15d012)
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